By Dr. Karl Theiler (auth.)
With the appearance of transgenic expertise, which permits the id of particular gene actions in constructing mammalian organisms, the home mouse has once more taken a vital position in experimental study as one of many genetically top understood mammals. greater than ever, molecular biologists are short of an in depth, standardized description of the anatomy of the constructing mouse embryo. during this vintage compendium, now cited so far and corrected, the writer provides each one degree of mouse improvement in images and micrographs utilizing hybrids of 2 inbred traces as a typical. Organ structures are systematically reconstructed from fertilization until eventually after beginning. Molecular biologists tracing the results of genetic manipulations, in addition to scholars and researchers of developmental biology, will relish the renewed availability of this commonplace reference paintings for its remarkable accuracy, its awareness to anatomical element, and the level of its documentation.
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Additional info for The House Mouse: Atlas of Embryonic Development
At the 6-somite stage a distinct lumen also appears in median sections (Fig. 82). At the same time, single mesodermal cells have joined to form an endocardial tube. This tube is continuous with the first aortic arch, which developed in situ along with the paired dorsal aortae. The dorsal aorta originates bilaterally in the trunk region, beneath the somite stalks, and is visible in many cross sections (Fig. 79). 34 Intestinal Tract The anlage of the foregut pouch has appeared in the preceding age group (Fig.
At the same time the omental bursa develops as a lateral peritoneal pocket (Fig. 124). Within the hepato-duodenal field, columns of cells (hepatic epithelial cords) continue to invade the mesenchymal tissue of the septum transversum. The pancreas develops from two separate areas of the duodenal epithelium. The anlage of the ventral pancreas is a small, circumscribed ventral evagination in the caudal part of the hepato-duodenal field. The dorsal pancreas, on the other hand, is a broad evagination in the dorsal half of the duodenal epithelium, which is not constricted until the end of this period (Fig.
O = otic invagination. KT 988, 15 somites. 11. 5: 1 FIG. 100. ). Aa = forelimb. 5:1 FIG. 101. Cross section through embryo, 8 days 21 h, 15 somites. Ao = aorta, Au = umbilical artery, H = hindgut. KT 987/1. 180:1 FIG. 102. Detail of Fig. 101, with somite 14. Ao = aorta; Vn = pronephric duct, without lumen here; Pt = peritoneal funnel. 350:1 FIG. 103. Cross section through same embryo, 15 somites, at the level of the facial nerve (N. VII). Vc. = vena capitis lateralis, Ao = aorta, V = foregut. KT 987/1.